Trehalose Dihydrate NF EP BP JP ChP

Pfanstiehl Multi-Compendial Trehalose dihydrate Key Benefits:

• Cellular Protection:
  Trehalose dihydrate by Pfanstiehl helps protect cells and biological materials from damage caused by freezing and thawing. When cells freeze, ice crystals can form and rupture cell membranes, causing damage. Trehalose prevents ice crystal formation, keeping cell membranes intact and maintaining the cell’s structure. It also helps protect proteins and lipids inside the cells, preserving their function. This makes Trehalose essential in preserving cell viability during cryopreservation.

• Protein Stabilization:
  Trehalose dihydrate by Pfanstiehl is well known for stabilizing proteins during freezing and thawing. Proteins can become damaged or lose shape when exposed to low temperatures which can cause issues like denaturation and clumping. Trehalose works by forming a protective layer around proteins that keeps them stable and maintains their proper structure. This is particularly important in protein-based drugs like vaccines, where the protein’s structure is critical for its effectiveness.

• Prevention of Freeze-Thaw Damage:
  Low endotoxin Trehalose is an effective cryoprotectant that reduces the harmful effects of freezing and thawing on biological materials. Freezing can cause ice crystals to form which damage cells and proteins. Trehalose prevents the formation of large ice crystals and minimizes damage. This is important for preserving biological samples and ensuring that cells and proteins remain intact and functional.

• Improved Viability and Functionality:
  Trehalose improves the survival and function of cells and biological molecules after thawing. Freezing can damage cells and reduce their effectiveness but trehalose protects them and ensures they retain their function when thawed. This is especially valuable for vaccines, antibodies and other biopharmaceutical products where maintaining the activity of the molecules is essential for successful treatment.

• Enhanced Long-Term Storage:
  Trehalose  helps store biological materials at very low temperatures for extended periods without losing their function. Long-term storage can cause biological products to degrade but Trehalose protects them from damage during freezing and dehydration. This is critical in the biotechnology and pharmaceutical industries where drug product must remain stable over time for use in vaccines or gene therapies.