Delivering on the Promise of Purity

D-Mannitol USP EP JP ChP

Mannitol is classified as a sugar alcohol and is derived from a sugar (mannose) by reduction.  Other widely known polyols are xylitol and sorbitol. Mannitol and sorbitol are isomers, differing only in the orientation of the hydroxyl group on carbon two.  The physical properties of mannitol make it suitable for use as a bulking agent in tableting.  However, it also has unique chemical properties that enable it to stabilize a wide variety of pharmaceutical preparations, including liquid formulations, as well as protect proteins from denaturation/degradation upon lyophilization, spray drying, and reconstitution.

Pfanstiehl Brand High Purity Low Endotoxin Mannitol was developed specifically for biopharmaceutical use, to the highest quality and purity standards.  It has been utilized as a key component to stabilize proteins during formulation, freeze drying, and finish/fill applications.

The various benefits imparted by Mannitol include but are not limited to:
•    Enhanced Protein Therapeutic Stability
•    Vaccine Stabilization
•    Carrier in Lyophilized & Spray Dried Formulations

Blue barrel of D-Mannitol

High Purity – Low Endotoxin – Low Metals – Parenteral Grade

Pfanstiehl Brand Mannitol is available as USP-NF (United States Pharmacopoeia—National Formulary), EP (European Pharmacopoeia), JP (Japanese Pharmacopoeia).

Product DescriptionProduct CodeCAS Number
D-Mannitol, High Purity Low Endotoxin USP, EP, JP, ChPM-109-769-65-8

Available Package Sizes: 1kg, 5kg, 25kg, 50kg

Development Samples: ~100g – Available upon request