L-Arginine is an essential amino acid that is physiologically active in the L-form. The amino acid L-Arginine is frequently used as a solution additive to help stabilize proteins against aggregation, particularly in the process of protein refolding. Amino acids have been known to exhibit both lyoprotective and cryoprotective effects similar to those of established stabilizers, such as sugars and/or polymers, but they offer a greater range of chemical structures and physicochemical properties. Their ability to prevent protein aggregation in both liquid and solid states, make them an attractive alternative as protein stabilizers for freeze drying. L-Arginine has a chemical structure and physicochemical characteristics which are distinct among amino acids and can provide additional benefits to freeze-dried protein formulations with regard to stability. Typically known and used as a key component in upstream cell culture, L-Arginine has also been utilized to help prevent aggregation of pharmaceutical formulations containing therapeutic proteins at relatively high concentrations.
Pfanstiehl Brand High Purity / Low Endotoxin-Low Metal Arginine establishes a new quality standard for amino acids, designed specifically for Biopharmaceutical and Pharmaceutical Production. Pfanstiehl Brand Arginine is available as USP (United States Pharmacopoeia), EP (European Pharmacopoeia), JP (Japanese Pharmacopoeia) and ChP (Chinese Pharmacopoeia).
|Product Description||Product Code||CAS Number|
|L-Arginine, High Purity / Low Endotoxin-Low Metals, USP/EP/JP/ChP||A-170||74-79-3|
|L-Arginine Hydrochloride, High Purity, Low Endotoxin, Low Metals, USP/EP/JP/ChP||A-171||1119-34-2|