{"id":4955,"date":"2024-05-21T11:35:56","date_gmt":"2024-05-21T11:35:56","guid":{"rendered":"https:\/\/pfanstiehl.com\/solutions\/formulazioni-ad-alta-concentrazione\/"},"modified":"2024-07-08T06:11:46","modified_gmt":"2024-07-08T06:11:46","slug":"formulazioni-ad-alta-concentrazione","status":"publish","type":"solutions","link":"https:\/\/pfanstiehl.com\/it\/solutions\/formulazioni-ad-alta-concentrazione\/","title":{"rendered":"Formulazioni ad alta concentrazione"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"4955\" class=\"elementor elementor-4955 elementor-456\" data-elementor-post-type=\"solutions\">\n\t\t\t\t<div class=\"elementor-element elementor-element-24f53088 e-flex e-con-boxed e-con e-parent\" data-id=\"24f53088\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-d124f80 e-flex e-con-boxed e-con e-child\" data-id=\"d124f80\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-216f275b elementor-widget elementor-widget-heading\" data-id=\"216f275b\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.23.0 - 05-08-2024 *\/\n.elementor-heading-title{padding:0;margin:0;line-height:1}.elementor-widget-heading .elementor-heading-title[class*=elementor-size-]>a{color:inherit;font-size:inherit;line-height:inherit}.elementor-widget-heading .elementor-heading-title.elementor-size-small{font-size:15px}.elementor-widget-heading .elementor-heading-title.elementor-size-medium{font-size:19px}.elementor-widget-heading .elementor-heading-title.elementor-size-large{font-size:29px}.elementor-widget-heading .elementor-heading-title.elementor-size-xl{font-size:39px}.elementor-widget-heading .elementor-heading-title.elementor-size-xxl{font-size:59px}<\/style><h1 class=\"elementor-heading-title elementor-size-default\">Soluzioni Pfanstiehl per la formulazione di anticorpi ad alta concentrazione<\/h1>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1bd54bf2 elementor-widget elementor-widget-text-editor\" data-id=\"1bd54bf2\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.23.0 - 05-08-2024 *\/\n.elementor-widget-text-editor.elementor-drop-cap-view-stacked .elementor-drop-cap{background-color:#69727d;color:#fff}.elementor-widget-text-editor.elementor-drop-cap-view-framed .elementor-drop-cap{color:#69727d;border:3px solid;background-color:transparent}.elementor-widget-text-editor:not(.elementor-drop-cap-view-default) .elementor-drop-cap{margin-top:8px}.elementor-widget-text-editor:not(.elementor-drop-cap-view-default) .elementor-drop-cap-letter{width:1em;height:1em}.elementor-widget-text-editor .elementor-drop-cap{float:left;text-align:center;line-height:1;font-size:50px}.elementor-widget-text-editor .elementor-drop-cap-letter{display:inline-block}<\/style>\t\t\t\t<p>Lo sviluppo di formulazioni di anticorpi ad alta concentrazione (HCAF) superiori a 100 mg\/ml \u00e8 essenziale per la creazione di terapie a base di anticorpi monoclonali (mAb) che possono essere somministrate per via sottocutanea. Tuttavia, l&#8217;inevitabile variabilit\u00e0 tra le molecole crea sfide tecniche complesse che richiedono un&#8217;ampia gamma di strumenti e competenze per essere risolte.  <\/p>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-263b929c e-flex e-con-boxed e-con e-child\" data-id=\"263b929c\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-45e34127 elementor-widget elementor-widget-image\" data-id=\"45e34127\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.23.0 - 05-08-2024 *\/\n.elementor-widget-image{text-align:center}.elementor-widget-image a{display:inline-block}.elementor-widget-image a img[src$=\".svg\"]{width:48px}.elementor-widget-image img{vertical-align:middle;display:inline-block}<\/style>\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"800\" height=\"491\" src=\"https:\/\/pfanstiehl.com\/wp-content\/uploads\/2024\/06\/sol-4-1024x629.png\" class=\"attachment-large size-large wp-image-2214\" alt=\"\" srcset=\"https:\/\/pfanstiehl.com\/wp-content\/uploads\/2024\/06\/sol-4-1024x629.png 1024w, https:\/\/pfanstiehl.com\/wp-content\/uploads\/2024\/06\/sol-4-300x184.png 300w, https:\/\/pfanstiehl.com\/wp-content\/uploads\/2024\/06\/sol-4-768x472.png 768w, https:\/\/pfanstiehl.com\/wp-content\/uploads\/2024\/06\/sol-4-600x368.png 600w, https:\/\/pfanstiehl.com\/wp-content\/uploads\/2024\/06\/sol-4.png 1140w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-464af55 solutions_content_box e-flex e-con-boxed e-con e-parent\" data-id=\"464af55\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-81986c7 e-flex e-con-boxed e-con e-child\" data-id=\"81986c7\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-37b8a322 elementor-widget elementor-widget-text-editor\" data-id=\"37b8a322\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<h4>Sfide di viscosit\u00e0 e solubilit\u00e0:<\/h4>\n<p>Uno dei principali ostacoli nello sviluppo di HCAF \u00e8 l&#8217;inevitabile aumento della viscosit\u00e0 della soluzione all&#8217;aumentare della concentrazione di anticorpi monoclonali. Questo aumento della viscosit\u00e0 pone sfide durante la filtrazione, il riempimento e altri processi di produzione. Inoltre, le soluzioni di anticorpi monoclonali altamente concentrate possono incontrare limitazioni di solubilit\u00e0, portando alla gelificazione o alla separazione di fase, specialmente in condizioni di refrigerazione. Tali eventi non solo mettono a repentaglio la stabilit\u00e0 della formulazione, ma minacciano anche l&#8217;efficacia terapeutica.<\/p>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-69a1ba89 e-flex e-con-boxed e-con e-child\" data-id=\"69a1ba89\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-4f1007fa elementor-widget elementor-widget-text-editor\" data-id=\"4f1007fa\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<h4>Sfide del processo di produzione:<\/h4>\n<p>Il processo di formulazione stesso crea sfide complesse, in particolare nelle operazioni unitarie come l&#8217;ultrafiltrazione-diafiltrazione, la filtrazione sterile e le fasi di riempimento-finitura. Queste sfide possono ostacolare l&#8217;efficienza della produzione e aumentare i costi, richiedendo soluzioni innovative per semplificare i processi senza compromettere la qualit\u00e0 del prodotto.<\/p>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-4abc820e e-flex e-con-boxed e-con e-child\" data-id=\"4abc820e\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-c7ff810 elementor-widget elementor-widget-text-editor\" data-id=\"c7ff810\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<h4>Problemi di siringabilit\u00e0 e iniettabilit\u00e0:<\/h4>\n<p>L&#8217;alta viscosit\u00e0 e l&#8217;aggregazione di anticorpi monoclonali non solo ostacolano i processi di produzione, ma compromettono anche la siringabilit\u00e0 e l&#8217;iniettabilit\u00e0 durante il parto del paziente. Questi problemi riducono la compliance del paziente e l&#8217;efficacia del trattamento, evidenziando l&#8217;importanza di formulazioni ottimizzate per una facile somministrazione.<\/p>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-230443da e-flex e-con-boxed e-con e-child\" data-id=\"230443da\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-15829f69 elementor-widget elementor-widget-text-editor\" data-id=\"15829f69\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<h4>Aggregazione proteica e stabilit\u00e0 all&#8217;immagazzinamento:<\/h4>\n<p>L&#8217;aggregazione proteica rappresenta un rischio significativo durante la produzione e la somministrazione, che pu\u00f2 portare a una diminuzione della potenza terapeutica. Inoltre, la formazione di aggregati aumenta il rischio di innescare risposte immunitarie anti-farmaco, sottolineando la necessit\u00e0 di mantenere la stabilit\u00e0 di conservazione a lungo termine preservando l&#8217;integrit\u00e0 della formulazione.<\/p>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-6a9163fc e-flex e-con-boxed e-con e-child\" data-id=\"6a9163fc\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-693d7bc elementor-widget elementor-widget-text-editor\" data-id=\"693d7bc\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<h4>Eccipienti e complessit\u00e0 della formulazione:<\/h4>\n<p>Gli eccipienti svolgono un ruolo fondamentale nel mitigare la viscosit\u00e0, migliorare la solubilit\u00e0 e garantire la stabilit\u00e0 nelle formulazioni HCAF. Tuttavia, selezionare gli eccipienti giusti mantenendo la stabilit\u00e0 della formulazione rimane un&#8217;arte mescolata con la scienza.  <\/p>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-2020c36e e-flex e-con-boxed e-con e-parent\" data-id=\"2020c36e\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-1063cfe5 elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"1063cfe5\" data-element_type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.23.0 - 05-08-2024 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var(--divider-color)}.elementor-widget-divider--separator-type-pattern{--divider-border-style:none}.elementor-widget-divider--separator-type-pattern.elementor-widget-divider--view-line .elementor-divider-separator,.elementor-widget-divider--separator-type-pattern:not(.elementor-widget-divider--view-line) .elementor-divider-separator:after,.elementor-widget-divider--separator-type-pattern:not(.elementor-widget-divider--view-line) .elementor-divider-separator:before,.elementor-widget-divider--separator-type-pattern:not([class*=elementor-widget-divider--view]) .elementor-divider-separator{width:100%;min-height:var(--divider-pattern-height);-webkit-mask-size:var(--divider-pattern-size) 100%;mask-size:var(--divider-pattern-size) 100%;-webkit-mask-repeat:var(--divider-pattern-repeat);mask-repeat:var(--divider-pattern-repeat);background-color:var(--divider-color);-webkit-mask-image:var(--divider-pattern-url);mask-image:var(--divider-pattern-url)}.elementor-widget-divider--no-spacing{--divider-pattern-size:auto}.elementor-widget-divider--bg-round{--divider-pattern-repeat:round}.rtl .elementor-widget-divider .elementor-divider__text{direction:rtl}.e-con-inner>.elementor-widget-divider,.e-con>.elementor-widget-divider{width:var(--container-widget-width,100%);--flex-grow:var(--container-widget-flex-grow)}<\/style>\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-43a2f69 e-flex e-con-boxed e-con e-parent\" data-id=\"43a2f69\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-6f3af571 elementor-widget elementor-widget-text-editor\" data-id=\"6f3af571\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<h3>Cosa pu\u00f2 fare Pfanstiehl per aiutare?<\/h3>\n<p>I Technical Sales Scientist di Pfanstiehl possono discutere con voi per comprendere le vostre sfide e fornire indicazioni basate sull&#8217;esperienza e sulle revisioni della letteratura per ridurre la viscosit\u00e0 e stabilizzare la struttura e l&#8217;attivit\u00e0 biologica della vostra proteina terapeutica.<\/p>\n<p>Aiutiamo a mettere insieme alcune idee per:<\/p>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-53349a58 solutions_content_box e-flex e-con-boxed e-con e-child\" data-id=\"53349a58\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-537e2e9a e-flex e-con-boxed e-con e-child\" data-id=\"537e2e9a\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-75102716 elementor-widget elementor-widget-text-editor\" data-id=\"75102716\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<h4>Agenti stabilizzanti:<\/h4><p>L&#8217;incorporazione di agenti stabilizzanti come zuccheri o polioli pu\u00f2 proteggere le proteine dalla denaturazione e dall&#8217;aggregazione durante lo stoccaggio e la manipolazione.<\/p><p><a href=\"https:\/\/pfanstiehl.com\/it\/categoria-prodotto\/sucrose-it\/\">Pfanstiehl HPLE-LM<sup>TM<\/sup> Saccarosio<\/a><br \/><a href=\"https:\/\/pfanstiehl.com\/it\/categoria-prodotto\/trehalose-it\/\">Pfanstiehl HPLE-LM<sup>TM<\/sup> Trealosio<\/a><br \/><a href=\"https:\/\/pfanstiehl.com\/it\/categoria-prodotto\/maltose-it\/\">Pfanstiehl HPLE-LM<sup>TM<\/sup> Maltosio<\/a><br \/><a href=\"https:\/\/pfanstiehl.com\/it\/categoria-prodotto\/d-mannitolo\/\">Pfanstiehl HPLE-LM<sup>TM<\/sup> Mannitolo<\/a><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-6cfb8826 e-flex e-con-boxed e-con e-child\" data-id=\"6cfb8826\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-50e4843d elementor-widget elementor-widget-text-editor\" data-id=\"50e4843d\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<h4>Utilizzo di eccipienti che riducono la viscosit\u00e0<\/h4><p>L&#8217;incorporazione di eccipienti che riducono la viscosit\u00e0 come arginina, cloruro di sodio o amminoacidi specifici pu\u00f2 mitigare l&#8217;aumento della viscosit\u00e0 mantenendo la stabilit\u00e0.<\/p><p><a href=\"https:\/\/pfanstiehl.com\/it\/categoria-prodotto\/arginine-it\/\">Pfanstiehl HPLE-LM<sup>TM<\/sup> L-Arginina<\/a><br \/><a href=\"https:\/\/pfanstiehl.com\/it\/categoria-prodotto\/arginina-hcl-it\/\">Pfanstiehl HPLE-LM<sup>TM<\/sup> L-Arginina HCL<\/a><br \/><a href=\"https:\/\/pfanstiehl.com\/it\/categoria-prodotto\/histidine-it\/\">Pfanstiehl HPLE-LM<sup>TM<\/sup>\u00a0L-istidina<\/a><br \/><a href=\"https:\/\/pfanstiehl.com\/it\/categoria-prodotto\/istidina-hcl\/\">Pfanstiehl HPLE-LM<sup>TM<\/sup>\u00a0L-istidina HCL<\/a><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-49c2453d e-flex e-con-boxed e-con e-child\" data-id=\"49c2453d\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-316d5370 elementor-widget elementor-widget-text-editor\" data-id=\"316d5370\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<h4>Ottimizzazione dei sistemi tampone:<\/h4><p>La regolazione del pH e della composizione del sistema tampone pu\u00f2 migliorare la solubilit\u00e0 e la stabilit\u00e0, fondamentali per le formulazioni ad alta concentrazione.<\/p><p><a href=\"https:\/\/pfanstiehl.com\/it\/categoria-prodotto\/tris-base-it\/\">Pfanstiehl HPLE-LM<sup>TM<\/sup> TRIS Base<\/a><br \/><a href=\"https:\/\/pfanstiehl.com\/it\/categoria-prodotto\/tris-hcl-it\/\">Pfanstiehl HPLE-LM<sup>TM<\/sup> Tris HCL<\/a><br \/><a href=\"https:\/\/pfanstiehl.com\/it\/categoria-prodotto\/succinato-di-sodio-esaidrato\/\">Pfanstiehl HPLE-LM<sup>TM<\/sup> Succinato di sodio<\/a><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-31f233cb e-flex e-con-boxed e-con e-parent\" data-id=\"31f233cb\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-2510ad33 elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"2510ad33\" data-element_type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-128d7df3 e-flex e-con-boxed e-con e-parent\" data-id=\"128d7df3\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-2a64ed02 elementor-widget elementor-widget-text-editor\" data-id=\"2a64ed02\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>Da oltre 100 anni, Pfanstiehl produce eccipienti, stabilizzanti e componenti tampone iniettabili cGMP che garantiscono un&#8217;elevata purezza e una bassa endotossina. I nostri componenti sono utilizzati nella maggior parte dei prodotti biofarmaceutici pi\u00f9 venduti al mondo e continuiamo a crescere ogni anno.  <\/p>\n<\/p>\n<p>I nostri clienti sanno che la combinazione del pluripremiato supporto tecnico di Pfanstiehl e dei componenti cGMP ad alta purezza e a basso contenuto di endotossine contribuir\u00e0 a garantire una migliore coerenza da un lotto all&#8217;altro e a ridurre il rischio di fallimento del lotto di produzione per la vostra terapia.<\/p>\n<\/p>\n<p>Se disponi di un farmaco biologico proteico o di un vaccino che richiede una formulazione di anticorpi ad alta concentrazione (HCAF), contattaci e saremo lieti di discutere di come possiamo lavorare insieme per rendere il tuo prodotto il pi\u00f9 di alta qualit\u00e0 possibile.<\/p>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-4aa77fc elementor-widget elementor-widget-button\" data-id=\"4aa77fc\" data-element_type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/pfanstiehl.com\/it\/contact-us\/\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Contattaci<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-7ecdf034 e-con-full right_fixed_btn e-flex e-con e-parent\" data-id=\"7ecdf034\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-6e2be36e fixed_desktop_btn elementor-widget elementor-widget-button\" data-id=\"6e2be36e\" data-element_type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/pfanstiehl.com\/it\/contact-us\/\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Contattaci<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-cd96f04 fixed_mobile_btn elementor-widget elementor-widget-button\" data-id=\"cd96f04\" data-element_type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/pfanstiehl.com\/it\/contact-us\/\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t<span class=\"elementor-button-icon\">\n\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-far-envelope\" viewBox=\"0 0 512 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M464 64H48C21.49 64 0 85.49 0 112v288c0 26.51 21.49 48 48 48h416c26.51 0 48-21.49 48-48V112c0-26.51-21.49-48-48-48zm0 48v40.805c-22.422 18.259-58.168 46.651-134.587 106.49-16.841 13.247-50.201 45.072-73.413 44.701-23.208.375-56.579-31.459-73.413-44.701C106.18 199.465 70.425 171.067 48 152.805V112h416zM48 400V214.398c22.914 18.251 55.409 43.862 104.938 82.646 21.857 17.205 60.134 55.186 103.062 54.955 42.717.231 80.509-37.199 103.053-54.947 49.528-38.783 82.032-64.401 104.947-82.653V400H48z\"><\/path><\/svg>\t\t\t<\/span>\n\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"featured_media":0,"menu_order":0,"template":"elementor_header_footer","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"_uf_show_specific_survey":0,"_uf_disable_surveys":false},"class_list":["post-4955","solutions","type-solutions","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - 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