{"id":4991,"date":"2024-05-21T10:47:22","date_gmt":"2024-05-21T10:47:22","guid":{"rendered":"https:\/\/pfanstiehl.com\/solutions\/stabilisation-des-vaccins-et-des-produits-biologiques\/"},"modified":"2024-07-05T07:47:30","modified_gmt":"2024-07-05T07:47:30","slug":"stabilisation-des-vaccins-et-des-produits-biologiques","status":"publish","type":"solutions","link":"https:\/\/pfanstiehl.com\/fr\/solutions\/stabilisation-des-vaccins-et-des-produits-biologiques\/","title":{"rendered":"Stabilisation des vaccins et des produits biologiques"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"4991\" class=\"elementor elementor-4991 elementor-363\" data-elementor-post-type=\"solutions\">\n\t\t\t\t<div class=\"elementor-element elementor-element-47c57ccb e-flex e-con-boxed e-con e-parent\" data-id=\"47c57ccb\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-74be739a e-flex e-con-boxed e-con e-child\" data-id=\"74be739a\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-61d9515c elementor-widget elementor-widget-heading\" data-id=\"61d9515c\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.23.0 - 05-08-2024 *\/\n.elementor-heading-title{padding:0;margin:0;line-height:1}.elementor-widget-heading .elementor-heading-title[class*=elementor-size-]>a{color:inherit;font-size:inherit;line-height:inherit}.elementor-widget-heading .elementor-heading-title.elementor-size-small{font-size:15px}.elementor-widget-heading .elementor-heading-title.elementor-size-medium{font-size:19px}.elementor-widget-heading .elementor-heading-title.elementor-size-large{font-size:29px}.elementor-widget-heading .elementor-heading-title.elementor-size-xl{font-size:39px}.elementor-widget-heading .elementor-heading-title.elementor-size-xxl{font-size:59px}<\/style><h1 class=\"elementor-heading-title elementor-size-default\">Solutions de stabilisation des vaccins et des produits biologiques de Pfanstiehl<\/h1>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-40ed537b elementor-widget elementor-widget-text-editor\" data-id=\"40ed537b\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.23.0 - 05-08-2024 *\/\n.elementor-widget-text-editor.elementor-drop-cap-view-stacked .elementor-drop-cap{background-color:#69727d;color:#fff}.elementor-widget-text-editor.elementor-drop-cap-view-framed .elementor-drop-cap{color:#69727d;border:3px solid;background-color:transparent}.elementor-widget-text-editor:not(.elementor-drop-cap-view-default) .elementor-drop-cap{margin-top:8px}.elementor-widget-text-editor:not(.elementor-drop-cap-view-default) .elementor-drop-cap-letter{width:1em;height:1em}.elementor-widget-text-editor .elementor-drop-cap{float:left;text-align:center;line-height:1;font-size:50px}.elementor-widget-text-editor .elementor-drop-cap-letter{display:inline-block}<\/style>\t\t\t\t<p>Les prot\u00e9ines contenues dans les formulations de produits biologiques et de vaccins sont des mol\u00e9cules sensibles qui peuvent subir une d\u00e9naturation, une agr\u00e9gation ou une d\u00e9gradation dans diverses conditions, telles que la temp\u00e9rature, les changements de pH ou le stress m\u00e9canique. La stabilisation des prot\u00e9ines est essentielle pour maintenir leur efficacit\u00e9 th\u00e9rapeutique, en particulier dans le d\u00e9veloppement de m\u00e9dicaments \u00e0 base de prot\u00e9ines et de produits biopharmaceutiques.<\/p>\n<p>Les prot\u00e9ines th\u00e9rapeutiques qui ne sont pas correctement stabilis\u00e9es peuvent pr\u00e9senter les d\u00e9fis suivants :<\/p>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-2e42849a e-flex e-con-boxed e-con e-child\" data-id=\"2e42849a\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-1480b180 elementor-widget elementor-widget-image\" data-id=\"1480b180\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.23.0 - 05-08-2024 *\/\n.elementor-widget-image{text-align:center}.elementor-widget-image a{display:inline-block}.elementor-widget-image a img[src$=\".svg\"]{width:48px}.elementor-widget-image img{vertical-align:middle;display:inline-block}<\/style>\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"800\" height=\"491\" src=\"https:\/\/pfanstiehl.com\/wp-content\/uploads\/2024\/06\/sol-1-1024x629.png\" class=\"attachment-large size-large wp-image-2211\" alt=\"\" srcset=\"https:\/\/pfanstiehl.com\/wp-content\/uploads\/2024\/06\/sol-1-1024x629.png 1024w, https:\/\/pfanstiehl.com\/wp-content\/uploads\/2024\/06\/sol-1-300x184.png 300w, https:\/\/pfanstiehl.com\/wp-content\/uploads\/2024\/06\/sol-1-768x472.png 768w, https:\/\/pfanstiehl.com\/wp-content\/uploads\/2024\/06\/sol-1-600x368.png 600w, https:\/\/pfanstiehl.com\/wp-content\/uploads\/2024\/06\/sol-1.png 1140w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-69b67200 solutions_content_box e-flex e-con-boxed e-con e-parent\" data-id=\"69b67200\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-20f5c4e3 e-flex e-con-boxed e-con e-child\" data-id=\"20f5c4e3\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-63b9ca28 elementor-widget elementor-widget-text-editor\" data-id=\"63b9ca28\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<h4>Perte d\u2019activit\u00e9 biologique :<\/h4>\n<p>L\u2019un des effets les plus critiques de la d\u00e9gradation des prot\u00e9ines est la perte potentielle d\u2019activit\u00e9 biologique. Les prot\u00e9ines d\u00e9pendent d\u2019une structure tridimensionnelle sp\u00e9cifique pour remplir leurs fonctions, et la d\u00e9gradation peut perturber cette structure, rendre la prot\u00e9ine inefficace ou r\u00e9duire consid\u00e9rablement son activit\u00e9.<\/p>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-28efd99e e-flex e-con-boxed e-con e-child\" data-id=\"28efd99e\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-12897de9 elementor-widget elementor-widget-text-editor\" data-id=\"12897de9\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<h4>Pharmacocin\u00e9tique alt\u00e9r\u00e9e :<\/h4>\nLa d\u00e9gradation des prot\u00e9ines peut entra\u00eener des changements dans la pharmacocin\u00e9tique du m\u00e9dicament, affectant des facteurs tels que l\u2019absorption, la distribution, le m\u00e9tabolisme et l\u2019excr\u00e9tion. Cela peut entra\u00eener un comportement impr\u00e9visible des m\u00e9dicaments dans le corps et peut avoir un impact sur les r\u00e9sultats th\u00e9rapeutiques souhait\u00e9s.\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-3af82d08 e-flex e-con-boxed e-con e-child\" data-id=\"3af82d08\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-4c98f755 elementor-widget elementor-widget-text-editor\" data-id=\"4c98f755\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<h4>Immunog\u00e9nicit\u00e9:<\/h4>\nLa d\u00e9gradation peut exposer des \u00e9pitopes cach\u00e9s ou induire des changements structurels qui rendent la prot\u00e9ine plus immunog\u00e8ne. Cela peut d\u00e9clencher une r\u00e9ponse immunitaire chez le patient, conduisant \u00e0 la formation d\u2019anticorps contre la prot\u00e9ine th\u00e9rapeutique. Les r\u00e9actions immunitaires peuvent r\u00e9duire l\u2019efficacit\u00e9 de la prot\u00e9ine et, dans certains cas, provoquer des effets ind\u00e9sirables.\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-329f704c e-flex e-con-boxed e-con e-child\" data-id=\"329f704c\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-383e76a7 elementor-widget elementor-widget-text-editor\" data-id=\"383e76a7\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<h4>Toxicit\u00e9 accrue :<\/h4>\nLes agr\u00e9gats visibles sont souvent per\u00e7us n\u00e9gativement d\u2019un point de vue marketing. Les patients et les cliniciens s\u2019attendent g\u00e9n\u00e9ralement \u00e0 ce que les produits injectables soient transparents et exempts de particules visibles. La pr\u00e9sence d\u2019agr\u00e9gats peut soulever des inqui\u00e9tudes quant \u00e0 l\u2019innocuit\u00e9 et \u00e0 l\u2019efficacit\u00e9 du produit.\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-624ac29c e-flex e-con-boxed e-con e-child\" data-id=\"624ac29c\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-1961e631 elementor-widget elementor-widget-text-editor\" data-id=\"1961e631\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<h4>Stabilit\u00e9 r\u00e9duite dans les formulations :<\/h4>\nLa d\u00e9gradation peut compromettre la stabilit\u00e9 de la prot\u00e9ine dans la formulation pharmaceutique. Cette instabilit\u00e9 peut entra\u00eener des changements physiques, tels que l\u2019agr\u00e9gation ou la pr\u00e9cipitation, qui peuvent r\u00e9duire davantage l\u2019efficacit\u00e9 du m\u00e9dicament.\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-7e9bbd60 e-flex e-con-boxed e-con e-child\" data-id=\"7e9bbd60\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-2eccf7f6 elementor-widget elementor-widget-text-editor\" data-id=\"2eccf7f6\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<h4>Dosage incoh\u00e9rent :<\/h4>\nLa d\u00e9gradation peut entra\u00eener des variations de la concentration de la prot\u00e9ine active dans le produit pharmaceutique. Un dosage incoh\u00e9rent peut avoir un impact sur la r\u00e9ponse th\u00e9rapeutique et peut entra\u00eener un sous-dosage ou un surdosage chez les patients.\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-7f59ab59 e-flex e-con-boxed e-con e-child\" data-id=\"7f59ab59\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-48de003 elementor-widget elementor-widget-text-editor\" data-id=\"48de003\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<h4>Perte de sp\u00e9cificit\u00e9 :<\/h4>\nLa d\u00e9gradation des prot\u00e9ines peut entra\u00eener une perte de sp\u00e9cificit\u00e9 pour la mol\u00e9cule ou le r\u00e9cepteur cible. Cette perte de sp\u00e9cificit\u00e9 peut r\u00e9duire la s\u00e9lectivit\u00e9 th\u00e9rapeutique, ce qui peut affecter le r\u00e9sultat th\u00e9rapeutique escompt\u00e9.\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-758c7066 e-flex e-con-boxed e-con e-child\" data-id=\"758c7066\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-6eb95c12 elementor-widget elementor-widget-text-editor\" data-id=\"6eb95c12\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<h4>\u00c9chec \u00e0 atteindre les objectifs th\u00e9rapeutiques :<\/h4>\nEn fin de compte, les effets cumulatifs de la d\u00e9gradation des prot\u00e9ines peuvent conduire \u00e0 l\u2019\u00e9chec du produit pharmaceutique \u00e0 atteindre ses objectifs th\u00e9rapeutiques pr\u00e9vus. Il s\u2019agit d\u2019une pr\u00e9occupation importante, en particulier dans le contexte des m\u00e9dicaments \u00e0 base de prot\u00e9ines o\u00f9 la pr\u00e9cision et la sp\u00e9cificit\u00e9 sont souvent essentielles\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-f1dfcb7 e-flex e-con-boxed e-con e-parent\" data-id=\"f1dfcb7\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-59dc2f2a elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"59dc2f2a\" data-element_type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.23.0 - 05-08-2024 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var(--divider-color)}.elementor-widget-divider--separator-type-pattern{--divider-border-style:none}.elementor-widget-divider--separator-type-pattern.elementor-widget-divider--view-line .elementor-divider-separator,.elementor-widget-divider--separator-type-pattern:not(.elementor-widget-divider--view-line) .elementor-divider-separator:after,.elementor-widget-divider--separator-type-pattern:not(.elementor-widget-divider--view-line) .elementor-divider-separator:before,.elementor-widget-divider--separator-type-pattern:not([class*=elementor-widget-divider--view]) .elementor-divider-separator{width:100%;min-height:var(--divider-pattern-height);-webkit-mask-size:var(--divider-pattern-size) 100%;mask-size:var(--divider-pattern-size) 100%;-webkit-mask-repeat:var(--divider-pattern-repeat);mask-repeat:var(--divider-pattern-repeat);background-color:var(--divider-color);-webkit-mask-image:var(--divider-pattern-url);mask-image:var(--divider-pattern-url)}.elementor-widget-divider--no-spacing{--divider-pattern-size:auto}.elementor-widget-divider--bg-round{--divider-pattern-repeat:round}.rtl .elementor-widget-divider .elementor-divider__text{direction:rtl}.e-con-inner>.elementor-widget-divider,.e-con>.elementor-widget-divider{width:var(--container-widget-width,100%);--flex-grow:var(--container-widget-flex-grow)}<\/style>\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-4761d847 e-flex e-con-boxed e-con e-parent\" data-id=\"4761d847\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-1a76f76c elementor-widget elementor-widget-text-editor\" data-id=\"1a76f76c\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<h3>Comment Pfanstiehl peut-il aider ?<\/h3>\n<p>Les scientifiques technico-commerciaux de Pfanstiehl peuvent discuter avec vous pour comprendre vos d\u00e9fis et vous fournir des conseils bas\u00e9s sur l\u2019exp\u00e9rience et les revues de litt\u00e9rature pour stabiliser la structure et l\u2019activit\u00e9 biologique des th\u00e9rapies. Le contr\u00f4le et la minimisation de la d\u00e9gradation sont essentiels pour maintenir l\u2019innocuit\u00e9, l\u2019efficacit\u00e9 et la qualit\u00e9 de ces m\u00e9dicaments.  <\/p>\n<\/p>\n<p>Laissez-nous vous aider \u00e0 rassembler quelques id\u00e9es pour :<\/p>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-c368ff5 elementor-widget elementor-widget-text-editor\" data-id=\"c368ff5\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<h5>Optimisation de la formulation :<\/h5>\n<ul>\n<li>Ajuster le pH : Maintenir les prot\u00e9ines \u00e0 leur pH optimal peut pr\u00e9venir la d\u00e9naturation.<\/li>\n<li>Tamponnage : Utilisation de tampons appropri\u00e9s pour maintenir une plage de pH stable.<\/li>\n<li>Ajouter des agents stabilisants : L\u2019inclusion d\u2019excipients comme les sucres, les polyols et les acides amin\u00e9s peut aider \u00e0 stabiliser les prot\u00e9ines.<\/li>\n<\/ul>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-813035a solutions_content_box e-flex e-con-boxed e-con e-child\" data-id=\"813035a\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-c96b560 e-flex e-con-boxed e-con e-child\" data-id=\"c96b560\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-68c14952 elementor-widget elementor-widget-text-editor\" data-id=\"68c14952\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<h4>Stabilisateurs<\/h4><p><a href=\"https:\/\/pfanstiehl.com\/fr\/categorie-produit\/saccharose-fr\/\">Pfanstiehl HPLE-LM<sup>TM<\/sup> Saccharose<\/a><br \/><a href=\"https:\/\/pfanstiehl.com\/fr\/categorie-produit\/trehalose-fr\/\">Pfanstiehl HPLE-LM<sup>TM<\/sup> Tr\u00e9halose<\/a><br \/><a href=\"https:\/\/pfanstiehl.com\/fr\/categorie-produit\/maltose-fr\/\">Pfanstiehl HPLE-LM<sup>TM<\/sup> Maltose<\/a><br \/><a href=\"https:\/\/pfanstiehl.com\/fr\/categorie-produit\/d-mannitol-fr\/\">Pfanstiehl HPLE-LM<sup>TM<\/sup> Mannitol<\/a><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-4c6e431a e-flex e-con-boxed e-con e-child\" data-id=\"4c6e431a\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-174617ca elementor-widget elementor-widget-text-editor\" data-id=\"174617ca\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<h4>Composants tampons<\/h4><p><a href=\"https:\/\/pfanstiehl.com\/fr\/categorie-produit\/tris-base-fr\/\">Pfanstiehl HPLE-LM<sup>TM<\/sup> TRIS Base<\/a><br \/><a href=\"https:\/\/pfanstiehl.com\/fr\/categorie-produit\/tris-hcl-fr\/\">Pfanstiehl HPLE-LM<sup>TM<\/sup> Tris HCL<\/a><br \/><a href=\"https:\/\/pfanstiehl.com\/fr\/categorie-produit\/succinate-de-sodium-hexahydrate\/\">Pfanstiehl HPLE-LM<sup>TM<\/sup> Succinate de sodium<\/a><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-7122149b e-flex e-con-boxed e-con e-child\" data-id=\"7122149b\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-3712f4fb elementor-widget elementor-widget-text-editor\" data-id=\"3712f4fb\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<h4>Cryoprotecteurs lyoprotecteurs<\/h4><p><a href=\"https:\/\/pfanstiehl.com\/fr\/categorie-produit\/saccharose-fr\/\">Pfanstiehl HPLE-LM<sup>TM<\/sup> Saccharose<\/a><br \/><a href=\"https:\/\/pfanstiehl.com\/fr\/categorie-produit\/trehalose-fr\/\">Pfanstiehl HPLE-LM<sup>TM<\/sup> Tr\u00e9halose<\/a><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-7af15e6 e-flex e-con-boxed e-con e-parent\" data-id=\"7af15e6\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-4bdc528e elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"4bdc528e\" data-element_type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-7d2a12d7 e-flex e-con-boxed e-con e-parent\" data-id=\"7d2a12d7\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-445166b0 elementor-widget elementor-widget-text-editor\" data-id=\"445166b0\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>Depuis plus de 100 ans, Pfanstiehl fabrique des excipients, des stabilisants et des composants tampons de qualit\u00e9 injectable cGMP qui garantissent une grande puret\u00e9 et une faible teneur en endotoxines. Nos composants sont utilis\u00e9s dans la majorit\u00e9 des produits pharmaceutiques les plus utilis\u00e9s au monde et nous continuons \u00e0 cro\u00eetre chaque ann\u00e9e.  <\/p>\n<\/p>\n<p>Nos clients savent que la combinaison du support technique prim\u00e9 de Pfanstiehl et des composants cGMP de haute puret\u00e9 \u00e0 faible teneur en endotoxines contribuera \u00e0 assurer une meilleure coh\u00e9rence d\u2019un lot \u00e0 l\u2019autre pour votre traitement et \u00e0 r\u00e9duire le risque d\u2019\u00e9chec de la fabrication des lots.<\/p>\n<\/p>\n<p>Si vous avez un produit biologique ou un vaccin prot\u00e9ique qui a besoin de technologies d\u2019excipient de stabilisation pour stabiliser votre prot\u00e9ine, veuillez nous contacter et nous serons heureux de discuter de la fa\u00e7on dont nous pouvons travailler ensemble pour rendre votre produit de la plus haute qualit\u00e9 possible.<\/p>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1f66e08e elementor-widget elementor-widget-button\" data-id=\"1f66e08e\" data-element_type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/pfanstiehl.com\/fr\/contactez-nous\/\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Contactez-nous<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-8ae18bb e-con-full right_fixed_btn e-flex e-con e-parent\" data-id=\"8ae18bb\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-5dacb54 fixed_desktop_btn elementor-widget elementor-widget-button\" data-id=\"5dacb54\" data-element_type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/pfanstiehl.com\/fr\/contactez-nous\/\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Contactez-nous<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-a1deb6e fixed_mobile_btn elementor-widget elementor-widget-button\" data-id=\"a1deb6e\" data-element_type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/pfanstiehl.com\/fr\/contactez-nous\/\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t<span class=\"elementor-button-icon\">\n\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-far-envelope\" viewBox=\"0 0 512 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M464 64H48C21.49 64 0 85.49 0 112v288c0 26.51 21.49 48 48 48h416c26.51 0 48-21.49 48-48V112c0-26.51-21.49-48-48-48zm0 48v40.805c-22.422 18.259-58.168 46.651-134.587 106.49-16.841 13.247-50.201 45.072-73.413 44.701-23.208.375-56.579-31.459-73.413-44.701C106.18 199.465 70.425 171.067 48 152.805V112h416zM48 400V214.398c22.914 18.251 55.409 43.862 104.938 82.646 21.857 17.205 60.134 55.186 103.062 54.955 42.717.231 80.509-37.199 103.053-54.947 49.528-38.783 82.032-64.401 104.947-82.653V400H48z\"><\/path><\/svg>\t\t\t<\/span>\n\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"featured_media":0,"menu_order":0,"template":"elementor_header_footer","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"_uf_show_specific_survey":0,"_uf_disable_surveys":false},"class_list":["post-4991","solutions","type-solutions","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - 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