{"id":73,"count":6,"description":"L-Histidine by Pfanstiehl is a naturally occurring amino acid that is widely used as an excipient in biologics manufacturing, most commonly as a buffer system to help maintain a stable pH in therapeutic protein formulations such as monoclonal antibodies. Because many biologics are sensitive to even small pH shifts\u2014which can accelerate aggregation, degradation, or loss of activity\u2014histidine-based buffers are often selected for their strong buffering capacity in the mildly acidic to near-neutral range and their compatibility with proteins. In downstream drug product manufacturing, L-histidine (and its salt form, histidine HCl) supports formulation stability and helps ensure consistent performance during processing steps like filtration and fill\/finish, as well as throughout long-term storage.","link":"https:\/\/pfanstiehl.com\/en\/high-purity-ingredients\/histidine\/","name":"L-Histidine","slug":"histidine","taxonomy":"product_cat","parent":0,"meta":[],"menu_order":0,"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>L-Histidine USP Excipient GMP, USP, EP, BP, JP, ChP - CAS 71-00-1 Pfanstiehl<\/title>\n<meta name=\"description\" content=\"L-Histidine USP Excipient GMP for Highest Purity, Lowest Endotoxin, Lowest Metals amino acids for enhanced buffering and stability of biologic formulations\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/pfanstiehl.com\/en\/high-purity-ingredients\/histidine\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"L-Histidine USP Excipient GMP, USP, EP, BP, JP, ChP - 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